New injection could 'transform' treatment of hypertension

INSUBCONTINENT EXCLUSIVE:
Drug trials are currently underway in the UK in what some experts have said is a huge breakthrough in treating high blood pressure
Just one injection every six months could lower high blood pressure, trial results suggest.The new drug, zilebesiran, developed by US-based
company Alnylam, is given as an injection rather than in traditional pill form.High blood pressure, or hypertension, rarely has noticeable
symptoms
But if untreated, it increases your risk of serious problems such as heart attacks and strokes.Persistent high blood pressure can increase
your risk of a number of serious and potentially life-threatening conditions, such as:heart diseaseheart attacksstrokesheart
failureperipheral arterial diseaseaortic aneurysmskidney diseasevascular dementiaThe Daily Mail reported that for the drug trials, 107
patients with hypertension were recruited to take part & 80 received a single injection of zilebesiran under the skin, while 32 received a
placebo containing no active ingredients.Five patients who initially received the placebo were later moved to zilebesiran.Analysis revealed
patients who received zilebesiran experienced a substantial reduction in systolic blood pressure & the force with which the heart pushes
blood out and round the body & which lasted up to six months.On average, systolic blood pressure lowered by over 10mmHg at a 200mg dose or
more of the drug, and more than 20mmHg at the highest dose of 800mg.A drop of this size can take someone with high blood pressure to within
a much safer range.Blood pressure naturally goes up and down throughout the course of the day, making it difficult to treat.But the study
found that the drop in blood pressure seen in patients who were treated with zilebesiran was consistent over 24 hours.The post New injection
could ‘revolutionize& treatment of high blood pressure first appeared on Ariana News.