INSUBCONTINENT EXCLUSIVE:
PRAYAGRAJ: Sinapic acid, commonly found in spices, fruits, - oils, especially in green - dry olive, could be used as a potential antidote to
dengue, a recent study has found.Undertaken by Amit Dubey, an alumnus of Allahabad University and his Malaysian counterpart Prof Aluwi, the
study has found place in 'Aspects Of Molecular Medicine' published by Netherland-based Elsevier, a Dutch academic publishing company
specializing in scientific, technical, and medical content."Amid the relentless battle against dengue virus, a global symphony of hope
Each year, 50-100 million individuals are stung by the virus, with 500,000 falling prey to severe dengue hemorrhagic fever, resulting in
20,000 fatalities," said Dubey, adding that Sinapic acid is a culinary marvel hidden in everyday delights including spices, citrus, berries,
vegetables, cereals, and olive oils.Sinapic acid derivatives showcase impressive interactions with DENV proteins, scoring well in a sort of
molecular docking experiment
"The present research focused on two compounds - 1-O-B-D-Glucopyranosyl Sinaoate and Sinapoyl Malate - which exhibited promising antiviral
effects against key proteins in the dengue virus
These compounds not only activated enzymes within the human body but also showed minimal harm in rat experiments, suggesting they could be
potential candidates for dengue treatment," he added.
