The Trump administration began mass layoffs of 10,000 staffers at US health agencies yesterday, according to multiple sources, with security guards barring entry to some employees just hours after they received dismissal notices.

Russia cannot accept US proposals to end the war in Ukraine in their current form because they do not address problems Moscow regards as having caused the conflict, a senior Russian diplomat said, suggesting US-Russia talks on the subject had stalled.

The makers of the artisan Cashel Blue cheese brand say its US market could halve under Donald Trump&s expected tariffs, but they are taking a long-term view on the matter and hope to expand into other markets.

An 11-year-old girl still missing after she entered the River Thames has been named by the Metropolitan Police as Kaliyah Coa.